Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
PCPG | rs1546593 | chr3:80592064 | T/C | 0.000124 | 177 | 19.87 | 24.03 | 27.4 | KM Plot |
PCPG | rs1551129 | chr2:2653008 | C/T | 1.04E-8 | 175 | 26.57 | 17.52 | 3.63 | KM Plot |
PCPG | rs15580 | chr6:26546048 | C/T | 6.12E-7 | 178 | 10.68 | 32.6 | 24.53 | KM Plot |
PCPG | rs1559552 | chr2:118670212 | T/C | 1.68E-5 | 177 | 25.28 | 30.93 | 11.65 | KM Plot |
PCPG | rs1560535 | chr2:236193395 | T/C | 2.6E-7 | 174 | 25.97 | 24.7 | 3.07 | KM Plot |
PCPG | rs1569134 | chr7:105158228 | T/C | 5.12E-5 | 178 | 20.2 | 29.43 | 2.28 | KM Plot |
PCPG | rs1571457 | chr10:131958960 | T/G | 0 | 178 | 25.53 | 24.47 | 3.17 | KM Plot |
PCPG | rs1581406 | chr2:209965670 | T/C | 1.34E-9 | 177 | 19.87 | 24.1 | 26.57 | KM Plot |
PCPG | rs1584300 | chr2:61586001 | A/C | 6.1E-5 | 178 | 24.1 | 30.18 | 10.3 | KM Plot |
PCPG | rs1584301 | chr2:61586132 | C/T | 2.81E-5 | 178 | 23.15 | 29.43 | 23.43 | KM Plot |
PCPG | rs1595735 | chr2:209971726 | T/A | 1.34E-9 | 177 | 19.87 | 24.1 | 26.57 | KM Plot |
PCPG | rs1602448 | chr13:64106818 | A/G | 6.87E-8 | 178 | 25.77 | 23.08 | 18.13 | KM Plot |
PCPG | rs162257 | chr17:3259421 | T/C | 0.000226 | 171 | 18.1 | 25.87 | 26.88 | KM Plot |
PCPG | rs162258 | chr17:3264180 | A/G | 0.000226 | 171 | 18.1 | 25.43 | 27.2 | KM Plot |
PCPG | rs1629583 | chr13:37654358 | G/A | 0.000303 | 176 | 4.17 | 23.88 | 25.97 | KM Plot |